Article
Association of a single nucleotide polymorphism in the TLR2 gene (rs3804099), but not in the TLR4 gene (rs4986790), with Helicobacter pylori infection and peptic ulcer.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 May 2018
Mirkamandar Ehsan, Nemati Maryam, Hayatbakhsh Mohammad Mehdi, Bassagh Arezu, Khosravimashizi Arezu, Jafarzadeh Abdollah
Abstract excerpt
BACKGROUND/AIMS: Toll-like receptors (TLRs), particularly TLR2 and TLR4, take part in elicitation of immune responses against Helicobacter pylori (H. pylori). This study aimed to investigate the relationship between single nucleotide polymorphisms (SNP) rs3804099 in the TLR2 gene and rs4986790 in the TLR4 gene with H. pylori infection and peptic ulcer (PU). MATERIALS AND METHODS: Blood specimens were obtained...
Topics
- Adult
- Antigens, Bacterial
- Bacterial Proteins
- Case-Control Studies
- Female
- Genotype
- Helicobacter Infections