Article
Association of polymorphism of TLR4 and CD14 genes with gastroduodenal diseases in Japan.
Inflammopharmacology - 1 Jun 2007
Tahara T, Arisawa T, Shibata T, Hirata I, Nakano H
Abstract excerpt
BACKGROUND: Host genetic factors may play a key role in determining the long-term outcome of the Helicobacter pylori infection. Toll like receptor 4(TLR4) and CD14-mediated recognition of lipo-polysaccharide (LPS) is required for efficient recognition of Gram-negative bacterial infections. AIMS: We investigated the effects of common polymorphisms of TLR4 Asp299Gly, Thr399Ile and CD14 promoter -C159T on the risk...
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