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Article

Association of Helicobacter pylori infection with Toll-like receptor-4 Thr399Ile polymorphism increased the risk of peptic ulcer development in North of Iran.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jan 2018

Tourani Mehdi, Habibzadeh Maryam, Shokri-Shirvani Javad, Teymournejad Omid, Mostafazadeh Amrollah, Khafri Soraya, Nouri Hamid Reza

Abstract excerpt

Toll-like receptor-4 (TLR4) polymorphisms may influence host immune response against Helicobacter pylori (H. pylori). This study aimed to investigate whether TLR4 polymorphisms are associated with H. pylori susceptibility and risk of peptic ulcer development or not. The TLR4 + 3725 G/C polymorphism was studied using polymerase chain reaction with confronting two-pair primers (PCR-CTPP). In addition, TLR4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29135054
DOI: 10.1111/apm.12779

Genes

TLR4

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