Article
Associations of a TLR4 single-nucleotide polymorphism with H. pylori associated gastric diseases in Iranian patients.
Clinics and research in hepatology and gastroenterology - 1 Jun 2014
Bagheri Nader, Azadegan-Dehkordi Fatemeh, Sanei Hosein, Taghikhani Afshin, Rahimian Ghorbanali, Salimzadeh Loghman, Hashemzadeh-Chaleshtori Morteza, Rafieian-kopaei Mahmoud, Shirzad Maryam, Shirzad Hedayatollah
Abstract excerpt
OBJECTIVE: Helicobacter pylori (H. pylori) is associated with gastric ulcer and gastric adenocarcinoma. Polymorphisms in the host genes coding for toll-like receptors (TLRs) may influence the innate and adaptive immune response to the infection, affecting the susceptibility to H. pylori or the disease outcomes. But the details and association to different polymorphisms and different clinical expressions in...
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