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Article

Genetic analysis of attenuation markers of cold-adapted X-31 influenza live vaccine donor strain.

Vaccine - 8 Mar 2016

Jang Yo Han, Jung Eun-Ju, Lee Kwang-Hee, Byun Young Ho, Yang Seung Won, Seong Baik Lin

Abstract excerpt

Cold-adapted live attenuated influenza vaccines (CAIVs) have been considered as a safe prophylactic measure to prevent influenza virus infections. The safety of a CAIV depends largely on genetic markers that confer specific attenuation phenotypes. Previous studies with other CAIVs reported that polymerase genes were primarily responsible for the attenuation. Here, we analyzed the genetic mutations and their...

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Identifiers

PMID: 26851733
DOI: 10.1016/j.vaccine.2016.01.053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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