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Article

[New cold-adapted donor strains for live influenza vaccine].

Voprosy virusologii - 1 Jan 2000

Gendon Iu Z, Markushin S G, Tsfasman T M, Akopova I I, Akhmatova N K, Koptiaeva I B

Abstract excerpt

Cold-adapted (CA) strains A/Krasnodar/35 and B/Victoria/63 were isolated using passages of A/Krasnodar/101/59 and B/Victoria/2/87 wild type strains at low temperatures. The resulting CA strains possessed TS and CA phenotypes and had a reduced ability to reproduce in mouse lungs and nasal turbinates. They displayed a high protective efficacy in experiments on mice. The two CA strains reproduced well in chick...

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PMID: 23785755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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