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Article

Genome-wide investigation of schizophrenia associated plasma Ndel1 enzyme activity.

Schizophrenia research - 1 Apr 2016

Gadelha Ary, Coleman Jonathan, Breen Gerome, Mazzoti Diego Robles, Yonamine Camila M, Pellegrino Renata, Ota Vanessa Kiyomi, Belangero Sintia Iole, Glessner Joseph, Sleiman Patrick, Hakonarson Hakon, Hayashi Mirian A F, Bressan Rodrigo A

Abstract excerpt

Ndel1 is a DISC1-interacting oligopeptidase that cleaves in vitro neuropeptides as neurotensin and bradykinin, and which has been associated with both neuronal migration and neurite outgrowth. We previously reported that plasma Ndel1 enzyme activity is lower in patients with schizophrenia (SCZ) compared to healthy controls (HCs). To our knowledge, no previous study has investigated the genetic factors associated...

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Source

Identifiers

PMID: 26851141
DOI: 10.1016/j.schres.2016.01.043

Genes

CCDC25
DISC1
MAGI2
ZFPM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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