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MAD1L1 and TSNARE gene polymorphisms are associated with schizophrenia susceptibility in the Han Chinese population.

BMC medical genomics - 4 Sept 2021

Liu Xianglai, Xie Hailing, Fu Zejuan, Yao Qiankun, Han Tianming, Zhan Dafei, Lin Zhan, Zhu Hong

Abstract excerpt

BACKGROUND: Schizophrenia (SCZ) is a severe mental illness with high heritability. This study aimed to explore the correlation between MAD1L1, TSNARE polymorphisms and SCZ susceptibility. METHODS: A total of 493 SCZ patients and 493 healthy controls were included. The genotypes of MAD1L1 and TSNARE polymorphisms were identified by Agena MassARRAY platform. Odds ratio (OR) and 95% confidence intervals (CIs) were...

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Identifiers

PMID: 34481484
DOI: 10.1186/s12920-021-01070-2
PMCID: PMC8418747

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