Article
Understanding the role of DISC1 in psychiatric disease and during normal development.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 14 Oct 2009
Brandon Nicholas J, Millar J Kirsty, Korth Carsten, Sive Hazel, Singh Karun K, Sawa Akira
Abstract excerpt
The biology of schizophrenia is complex with multiple hypotheses (dopamine, glutamate, neurodevelopmental) well supported to underlie the disease. Pathways centered on the risk factor "disrupted in schizophrenia 1" (DISC1) may be able to explain and unite these disparate hypotheses and will be the topic of this mini-symposium preview. Nearly a decade after its original identification at the center of a...
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