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Article

Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1).

Neurochemistry international - 1 Jan 2000

Matsuzaki Shinsuke, Tohyama Masaya

Abstract excerpt

Disrupted-in-schizophrenia 1 (DISC1) is a gene disrupted by a (1:1) (q42.1;q14.3) translocation that segregates with major psychiatric disorders in a Scottish family. To elucidate how DISC1 confers susceptibility to psychiatric disorders, identification of the molecules, which bind to the domain close to the translocation breakpoint in the DISC1 gene, was performed and fasciculation and elongation protein zeta-1...

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Source

Identifiers

PMID: 17664024
DOI: 10.1016/j.neuint.2007.06.018

Genes

DISC1
NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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