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Article

DISCopathies: brain disorders related to DISC1 dysfunction.

Reviews in the neurosciences - 1 Jan 2009

Korth Carsten

Abstract excerpt

During the last decade, disrupted-in-schizophrenia 1 (DISC1) has emerged as a protein involved in the pathogenesis of chronic mental diseases such as schizophrenia, or recurrent affective disorders. Its multiple functions include regulating corticogenesis, synapse integrity and adult neurogenesis, indicating a key role in the hard-wiring and the maintenance of communicative abilities of the brain. From its...

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Source

Identifiers

PMID: 20397618
DOI: 10.1515/revneuro.2009.20.5-6.321

Genes

DISC1
NDE1
NDEL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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