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Article

FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.

Oncotarget - 1 Mar 2016

Chougule Rohit A, Kazi Julhash U, Rönnstrand Lars

Abstract excerpt

FYN is a non-receptor tyrosine kinase belonging to the SRC family of kinases, which are frequently over-expressed in human cancers, and play key roles in cancer biology. SRC has long been recognized as an important oncogene, but little attention has been given to its other family members. In this report, we have studied the role of FYN in FLT3 signaling in respect to acute myeloid leukemia (AML). We observed that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Leukemia, Myeloid

Share to Proto-Oncogene Proteins c-fyn

Share to STAT5 Transcription Factor

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Source

Open in PubMed Open full text

Identifiers

PMID: 26848862
DOI: 10.18632/oncotarget.7128
PMCID: PMC4891096

Genes

FYN
FLT3
SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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