Article
Understanding the cellular roles of Fyn-related kinase (FRK): implications in cancer biology.
Cancer metastasis reviews - 1 Jun 2016
Goel Raghuveera Kumar, Lukong Kiven Erique
Abstract excerpt
The non-receptor tyrosine kinase Fyn-related kinase (FRK) is a member of the BRK family kinases (BFKs) and is distantly related to the Src family kinases (SFKs). FRK was first discovered in 1993, and studies pursued thereafter attributed a potential tumour-suppressive function to the enzyme. In recent years, however, further functional characterization of the tyrosine kinase in diverse cancer types suggests that...
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