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Article

FYN: emerging biological roles and potential therapeutic targets in cancer

5 Feb 2023

Abstract excerpt

Src family protein kinases (SFKs) play a key role in cell adhesion, invasion, proliferation, survival, apoptosis, and angiogenesis during tumor development. In humans, SFKs consists of eight family members with similar structure and function. There is a high level of overexpression or hyperactivity of SFKs in tumor, and they play an important role in multiple signaling pathways involved in tumorigenesis. FYN is a...

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PMID: 36740671
DOI: 10.1186/s12967-023-03930-0

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