Article
SFK-STAT pathway: an alternative and important way to malignancies.
Annals of the New York Academy of Sciences - 1 Nov 2006
Hayakawa Fumihiko, Naoe Tomoki
Abstract excerpt
Signal transducers and activators of transcription (STAT) proteins play a crucial role in mediating signals from a diverse spectrum of cytokine receptors. STAT is thought to be activated by JAK family kinases (JFK) in many cytokine receptor signal pathways; however, recent studies have demonstrated an alternative pathway to activate STAT by Src family kinases (SFK) in growth factor receptor signal. We also...
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