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Article

A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria.

PloS one - 1 Jan 2016

Mariotti-Ferrandiz Encarnita, Pham Hang-Phuong, Dulauroy Sophie, Gorgette Olivier, Klatzmann David, Cazenave Pierre-André, Pied Sylviane, Six Adrien

Abstract excerpt

Cerebral Malaria (CM) is associated with a pathogenic T cell response. Mice infected by P. berghei ANKA clone 1.49 (PbA) developing CM (CM+) present an altered PBL TCR repertoire, partly due to recurrently expanded T cell clones, as compared to non-infected and CM- infected mice. To analyse the relationship between repertoire alteration and CM, we performed a kinetic analysis of the TRBV repertoire during the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26844551
DOI: 10.1371/journal.pone.0147871
PMCID: PMC4742225

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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