Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TCRβ-expressing macrophages induced by a pathogenic murine malaria correlate with parasite burden and enhanced phagocytic activity

25 Jul 2018

Abstract excerpt

Macrophages express a wide array of invariant receptors that facilitate host defense and mediate pathogenesis during pathogen invasion. We report on a novel population of CD11bhighCD14+F4/80+ macrophages that express TCRβ. This population expands dramatically during a Plasmodium berghei ANKA infection and sequesters in the brain during experimental cerebral malaria. Importantly, measurement of TCRβ transcript and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30044851
DOI: 10.1371/journal.pone.0201043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TCRβ-expressing macrophages induced by a pathogenic murine malaria correlate with parasite burden and enhanced phagocytic activityPMID 30044851Read ↗

A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria.Semantic proximity Read ↗

γδ-T cells promote IFN-γ–dependent Plasmodium pathogenesis upon liver-stage infectionSemantic proximity Read ↗

Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral MalariaSemantic proximity Read ↗

Selective Upregulation of Transcripts for Six Molecules Related to T Cell Costimulation and Phagocyte Recruitment and Activation among 734 Immunity-Related Genes in the Brain during Perforin-Dependent, CD8 + T Cell-Mediated Elimination of Toxoplasma gondii CystsSemantic proximity Read ↗

Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestrationSemantic proximity Read ↗

Pathogenic roles of CD14, galectin-3, and OX40 during experimental cerebral malaria in mice.Semantic proximity Read ↗

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral MalariaSemantic proximity Read ↗

On the Pathogenic Role of Brain-Sequestered αβ CD8+ T Cells in Experimental Cerebral MalariaSemantic proximity Read ↗

Development of a Novel CD4 <sup>+</sup> TCR Transgenic Line that Reveals a Dominant Role for CD8 <sup>+</sup> DC and CD40-Signaling in the Generation of Helper and CTL Responses to Blood Stage MalariaSemantic proximity Read ↗

Protective and pathogenic roles of CD8+ T cells during malaria infectionSemantic proximity Read ↗

Increased resistance to malaria in mice with methylenetetrahydrofolate reductase (Mthfr) deficiency suggests a mechanism for selection of the MTHFR 677C>T (c.665C>T) variant.Semantic proximity Read ↗

CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.