Article
Molecular correlates of experimental cerebral malaria detectable in whole blood.
Infection and immunity - 1 Mar 2011
Oakley Miranda S, Anantharaman Vivek, Venancio Thiago M, Zheng Hong, Mahajan Babita, Majam Victoria, McCutchan Thomas F, Myers Timothy G, Aravind L, Kumar Sanjai
Abstract excerpt
Cerebral malaria (CM) is a primary cause of deaths caused by Plasmodium falciparum in young children in sub-Saharan Africa. Laboratory tests based on early detection of host biomarkers in patient blood would help in the prognosis and differential diagnosis of CM. Using the Plasmodium berghei ANKA murine model of experimental cerebral malaria (ECM), we have identified over 300 putative diagnostic biomarkers of ECM...
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