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Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria

24 Jul 2019

Abstract excerpt

CD8+ T cells have been shown to play a critical role in the pathogenesis of experimental cerebral malaria (ECM) in mice, but their role in development of human cerebral malaria (HCM) remains unclear. Thus, in this study we have provided the first direct contrast of the accumulation of CD8+ T cells in the brain during HCM and ECM. HCM cases were from children who died of Plasmodium falciparum cerebral malaria at...

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Identifiers

PMID: 31396236
DOI: 10.3389/fimmu.2019.01747

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