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Article

Rapid Evolution of Citrate Utilization by Escherichia coli by Direct Selection Requires citT and dctA.

Journal of bacteriology - 1 Feb 2016

Van Hofwegen Dustin J, Hovde Carolyn J, Minnich Scott A

Abstract excerpt

The isolation of aerobic citrate-utilizing Escherichia coli (Cit(+)) in long-term evolution experiments (LTEE) has been termed a rare, innovative, presumptive speciation event. We hypothesized that direct selection would rapidly yield the same class of E. coli Cit(+) mutants and follow the same genetic trajectory: potentiation, actualization, and refinement. This hypothesis was tested with wild-type E. coli...

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Identifiers

PMID: 26833416
DOI: 10.1128/JB.00831-15
PMCID: PMC4800869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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