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Article

Evolution in Long-Term Stationary-Phase Batch Culture: Emergence of Divergent Escherichia coli Lineages over 1,200 Days.

mBio - 26 Jan 2021

Ratib Nicole R, Seidl Fabian, Ehrenreich Ian M, Finkel Steven E

Abstract excerpt

In natural environments, bacteria survive conditions of starvation and stress. Long-term batch cultures are an excellent laboratory system to study adaptation during nutrient stress because cells can incubate for months to years without the addition of nutrients. During long-term batch culture, cells adapt to acquire energy from cellular detritus, creating a complex and dynamic environment for mutants of...

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Identifiers

PMID: 33500336
DOI: 10.1128/mBio.03337-20
PMCID: PMC7858067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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