Article
Innovation in an E. coli evolution experiment is contingent on maintaining adaptive potential until competition subsides.
PLoS genetics - 1 Apr 2018
Leon Dacia, D'Alton Simon, Quandt Erik M, Barrick Jeffrey E
Abstract excerpt
Key innovations are disruptive evolutionary events that enable a species to escape constraints and rapidly diversify. After 15 years of the Lenski long-term evolution experiment with Escherichia coli, cells in one of the twelve populations evolved the ability to utilize citrate, an abundant but previously untapped carbon source in the environment. Descendants of these cells became dominant in the population and...
Topics
- Adaptation, Physiological
- Citric Acid
- Culture Media
- Directed Molecular Evolution
- Ecosystem
- Escherichia coli
- Escherichia coli Proteins
- Evolution, Molecular
- Gene Knock-In Techniques
- Genes, Bacterial