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Revisiting the Design of the Long-Term Evolution Experiment with Escherichia coli.

Journal of molecular evolution - 1 Jun 2023

Lenski Richard E

Abstract excerpt

The long-term evolution experiment (LTEE) with Escherichia coli began in 1988 and it continues to this day, with its 12 populations having recently reached 75,000 generations of evolution in a simple, well-controlled environment. The LTEE was designed to explore open-ended questions about the dynamics and repeatability of phenotypic and genetic evolution. Here I discuss various aspects of the LTEE's experimental...

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PMID: 36790511
DOI: 10.1007/s00239-023-10095-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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