Article
Characterization of acetic acid-detoxifying Escherichia coli evolved under phosphate starvation conditions.
Microbial cell factories - 19 Feb 2016
Moreau Patrice L, Loiseau Laurent
Abstract excerpt
BACKGROUND: During prolonged incubation of Escherichia coli K-12 in batch culture under aerobic, phosphate (Pi) starvation conditions, excess glucose is converted into acetic acid, which may trigger cell death. Following serial cultures, we isolated five evolved strains in two populations that survived prolonged incubation. METHODS: We sequenced the genomes of the ancestral and evolved strains, and determined the...
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