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Article

Genomic analysis of a key innovation in an experimental Escherichia coli population.

Nature - 27 Sept 2012

Blount Zachary D, Barrick Jeffrey E, Davidson Carla J, Lenski Richard E

Abstract excerpt

Evolutionary novelties have been important in the history of life, but their origins are usually difficult to examine in detail. We previously described the evolution of a novel trait, aerobic citrate utilization (Cit(+)), in an experimental population of Escherichia coli. Here we analyse genome sequences to investigate the history and genetic basis of this trait. At least three distinct clades coexisted for more...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22992527
DOI: 10.1038/nature11514
PMCID: PMC3461117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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