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Article

Adaptation of Escherichia coli to long-term batch culture in various rich media.

Research in microbiology - 1 Apr 2018

Westphal Lacey L, Lau Jasmine, Negro Zuly, Moreno Ivan J, Ismail Mohammed Wazim, Lee Heewook, Tang Haixu, Finkel Steven E, Kram Karin E

Abstract excerpt

Experimental evolution studies have characterized the genetic strategies microbes utilize to adapt to their environments, mainly focusing on how microbes adapt to constant and/or defined environments. Using a system that incubates Escherichia coli in different complex media in long-term batch culture, we have focused on how heterogeneity and environment affects adaptive landscapes. In this system, there is no...

Topics

Adaptation, Biological
Alleles
Batch Cell Culture Techniques
Culture Media
Epistasis, Genetic
Escherichia coli
Gene Frequency
Gene-Environment Interaction
Genetic Fitness
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nutritional Physiological Phenomena

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Identifiers

PMID: 29454026
DOI: 10.1016/j.resmic.2018.01.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-29454026-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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