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Genome evolution of Acinetobacter baylyi ADP1 during laboratory domestication: acquired mutations impact competence and metabolism.

Applied and environmental microbiology - 17 Sept 2025

Gifford Isaac, Vergis Meghna R, Barrick Jeffrey E

Abstract excerpt

The bacterium Acinetobacter baylyi is a model organism known for its extreme natural competence and metabolic versatility. It is capable of taking up environmental DNA at a high rate across all growth phases. The type strain ADP1 was created by random mutagenesis of a precursor strain, BD4, to prevent it from forming cell chains in culture. ADP1 has since been distributed between research groups over several...

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PMID: 40827875
DOI: 10.1128/aem.00936-25
PMCID: PMC12442408

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