Article
A full Bayesian partition model for identifying hypo- and hyper-methylated loci from single nucleotide resolution sequencing data.
BMC bioinformatics - 11 Jan 2016
Wang Henan, He Chong, Kushwaha Garima, Xu Dong, Qiu Jing
Abstract excerpt
BACKGROUD: DNA methylation is an epigenetic modification that plays important roles on gene regulation. Study of whole-genome bisulfite sequencing and reduced representation bisulfite sequencing brings the availability of DNA methylation at single CpG resolution. The main interest of study on DNA methylation data is to test the methylation difference under two conditions of biological samples. However, the high...
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