Article
Nonparametric Bayesian clustering to detect bipolar methylated genomic loci.
BMC bioinformatics - 16 Jan 2015
Wu Xiaowei, Sun Ming-An, Zhu Hongxiao, Xie Hehuang
Abstract excerpt
BACKGROUND: With recent development in sequencing technology, a large number of genome-wide DNA methylation studies have generated massive amounts of bisulfite sequencing data. The analysis of DNA methylation patterns helps researchers understand epigenetic regulatory mechanisms. Highly variable methylation patterns reflect stochastic fluctuations in DNA methylation, whereas well-structured methylation patterns...
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