Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early-Stage Induction of SWI/SNF Mutations during Esophageal Squamous Cell Carcinogenesis.

PloS one - 1 Jan 2016

Nakazato Hidetsugu, Takeshima Hideyuki, Kishino Takayoshi, Kubo Emi, Hattori Naoko, Nakajima Takeshi, Yamashita Satoshi, Igaki Hiroyasu, Tachimori Yuji, Kuniyoshi Yukio, Ushijima Toshikazu

Abstract excerpt

The SWI/SNF chromatin remodeling complex is frequently inactivated by somatic mutations of its various components in various types of cancers, and also by aberrant DNA methylation. However, its somatic mutations and aberrant methylation in esophageal squamous cell carcinomas (ESCCs) have not been fully analyzed. In this study, we aimed to clarify in ESCC, what components of the SWI/SNF complex have somatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Chromosomal Proteins, Non-Histone

Share to CpG Islands

Share to DNA, Neoplasm

Share to Esophageal Neoplasms

Share to Site-Specific DNA-Methyltransferase (Adenine-Specific)

Source

Open in PubMed Open full text

Identifiers

PMID: 26812616
DOI: 10.1371/journal.pone.0147372
PMCID: PMC4728064

Genes

PBRM1
SMARCA4
ARID2
ATRX
SMARCAL1
SMARCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early-Stage Induction of SWI/SNF Mutations during Esophageal Squamous Cell Carcinogenesis.PMID 26812616Read ↗

Comprehensive Immunohistochemical Study of the SWI/SNF Complex Expression Status in Gastric Cancer Reveals an Adverse Prognosis of SWI/SNF Deficiency in Genomically Stable Gastric CarcinomasSemantic proximity Read ↗

SWI/SNF chromatin remodeling and human malignancies.Semantic proximity Read ↗

Chromatin remodeling and cancer: the critical influence of the SWI/SNF complex.Semantic proximity Read ↗

SWI/SNF chromatin remodeling complexes and cancer.Semantic proximity Read ↗

The spectrum of SWI/SNF mutations, ubiquitous in human cancers.Semantic proximity Read ↗

The role of SWI/SNF complexes in digestive system neoplasms.Semantic proximity Read ↗

Role of SWI/SNF chromatin remodeling genes in lung cancer developmentSemantic proximity Read ↗

Research progress of SWI/SNF complex in breast cancer.Semantic proximity Read ↗

The SWI/SNF complex subunit genes: Their functions, variations, and links to risk and survival outcomes in human cancers.Semantic proximity Read ↗

Advances in the role of SWI/SNF complexes in tumours.Semantic proximity Read ↗

Molecular pathways: SWI/SNF (BAF) complexes are frequently mutated in cancer--mechanisms and potential therapeutic insights.Semantic proximity Read ↗

The SWI/SNF complex in cancer - biology, biomarkers and therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.