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Article

Role of SWI/SNF chromatin remodeling genes in lung cancer development

19 May 2022

Abstract excerpt

SWI/SNF family of chromatin remodeling complexes uses the energy of ATP to change the structure of DNA, playing key roles in DNA regulation and repair. It is estimated that up to 25% of all human cancers contain alterations in SWI/SNF, although the precise molecular mechanisms for their involvement in tumor progression are largely unknown. Despite the improvements achieved in the last decades on our knowledge of...

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PMID: 35587173
DOI: 10.1042/bst20211084

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