Article
The GATA3 gene is involved in leprosy susceptibility in Brazilian patients.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2016
Medeiros Priscila, da Silva Weber Laurentino, de Oliveira Gimenez Bruna Beatriz, Vallezi Keren Bastos, Moraes Milton Ozório, de Souza Vânia Niéto Brito, Latini Ana Carla Pereira
Abstract excerpt
Leprosy outcome is a complex trait and the host-pathogen-environment interaction defines the emergence of the disease. Host genetic risk factors have been successfully associated to leprosy. The 10p13 chromosomal region was linked to leprosy in familial studies and GATA3 gene is a strong candidate to be part of this association. Here, we tested tag single nucleotide polymorphisms at GATA3 in two case-control...
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