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Functional polymorphisms of Monocyte Chemoattractant Protein-1 gene and Pott's disease risk.

Immunobiology - 1 Mar 2016

Mecabih Fethi, Sadouki Fatiha, Bennabi Meriem, Salah Sofiane, Boukouaci Wahid, Amroun Habiba, Fortier Catherine, Marzais François, Charron Dominique, Djoudi Hachemi, Abbadi Mohamed Cherif, Krishnamoorthy Rajagopal, Tamouza Ryad

Abstract excerpt

OBJECTIVE: Monocyte Chemoattractant Protein-1 (MCP-1/CCL2), a key player in immune-mediated responses against Mycobacterium tuberculosis, is encoded by a polymorphic gene. Functionally relevant polymorphic variations in the MCP-1 gene have been associated with both susceptibility to and protection against tuberculosis-related disorders. Here, we investigated the potential impact of some of these polymorphisms on...

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Identifiers

PMID: 26626202
DOI: 10.1016/j.imbio.2015.11.004

Genes

CCL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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