Article
Identification of novel genetic loci GAL3ST4 and CHGB involved in susceptibility to leprosy.
Scientific reports - 27 Nov 2017
Yuan Youhua, You Yuangang, Wen Yan, Liu Jian, Li Huanying, Zhang Yumeng, Wu Nan, Liu Shuang, Zhang Shanshan, Chen Jiazhen, Ai Jingwen, Zhang Wenhong, Zhang Ying
Abstract excerpt
Leprosy has long been thought to have a strong genetic component, and so far, only positional cloning and genomewide association studies have been used to study the genetic susceptibility to leprosy,while whole exome sequencing (WES) approach has not yet been applied. In this study, we used WES approach on four leprosy patients and four healthy control relatives from two leprosy families. We found three new...
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