Article
Genetics of host response in leprosy.
Leprosy review - 1 Sept 2006
Moraes Milton Ozório, Cardoso Cynthia Chester, Vanderborght Patrícia Rosa, Pacheco Antônio Guilherme
Abstract excerpt
In this review, we discuss recently accumulated data, analysing genetic influence on leprosy outcome. Most leprosy-related epidemiological studies are based on the comparison of frequencies of genetic markers in case-control designs using candidate genes, mainly on immunological pathways. Genomic scans using family-based designs also identified some chromosome regions to be tested for association with leprosy....
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