Article
Association analysis of monocyte chemotactic protein-3 (MCP3) polymorphisms with asthmatic phenotypes.
Journal of biochemistry and molecular biology - 31 Jan 2005
Park Byung Lae, Kim Lyoung Hyo, Choi Yoo Hyun, Cheong Hyun Sub, Park Hae-Sim, Hong Soo-Jong, Choi Byoung Whui, Lee June-Hyuk, Uh Soo-Taek, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
The monocyte chemotactic protein-3 (MCP3), on chromosome 17q11.2-q12, is a secreted chemokine, which attracts macrophages during inflammation and metastasis. In an effort to discover additional polymorphism(s) in genes whose variant(s) have been implicated in asthma, we scrutinized the genetic polymorphisms in MCP3 to evaluate it as a potential candidate gene for asthma host genetic study. By direct DNA...
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