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Article

Lack of association between polymorphisms in the SIRT6 gene and longevity in a Chinese population.

Molecular and cellular probes - 1 Apr 2016

Lin Rong, Zhang Yunxia, Yan Dongjing, Liao Xiaoping, Gong Gu, Hu Junjie, Fu Yunxin, Cai Wangwei

Abstract excerpt

Sirtuin 6 (SIRT6) has recently been demonstrated to play an important role in the regulation of longevity in mammals. We therefore aimed to determine whether common variations in the SIRT6 gene are associated with human longevity. Five tag single nucleotide polymorphisms (SNPs) across the SIRT6 gene and its 5 kb up-/downstream region, including rs350852, rs350844, rs352493, rs4807546 and rs3760905, have been...

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Share to Aged, 80 and over
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Source

Identifiers

PMID: 26802595
DOI: 10.1016/j.mcp.2016.01.005

Genes

SIRT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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