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Article

Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study "Treviso Longeva (TRELONG)".

Age (Dordrecht, Netherlands) - 1 Feb 2014

Albani Diego, Ateri Eleonora, Mazzuco Stefano, Ghilardi Alice, Rodilossi Serena, Biella Gloria, Ongaro Fausta, Antuono Piero, Boldrini Paolo, Di Giorgi Enrico, Frigato Andrea, Durante Elisabetta, Caberlotto Livio, Zanardo Andrea, Siculi Marinella, Gallucci Maurizio, Forloni Gianluigi

Abstract excerpt

Human sirtuins are seven proteins with deacetylase activity that are emerging as key modulators of basic physiological functions. Some evidence links SIRT3 to longevity in mammals. This study aimed to investigate whether variants within SIRT3 gene were associated to human longevity. We analyzed 549 genomic DNA collected during the prospective study "Treviso Longeva," including elderly over 70 years of age from...

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Identifiers

PMID: 23839864
DOI: 10.1007/s11357-013-9559-2
PMCID: PMC3889902

Genes

SIRT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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