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Article

Frequency and distribution of FCN2 and FCN3 functional variants among MBL2 genotypes.

Immunogenetics - 1 May 2016

Bjarnadottir Helga, Arnardottir Margret, Ludviksson Bjorn Runar

Abstract excerpt

The six types of pattern recognition molecules (PRMs) that initiate complement via the lectin pathway (LP) comprise collectins and ficolins. The importance of having various PRMs to initiate the LP is currently unclear. Mannan-binding lectin (MBL) is a collectin member of the LP PRMs. MBL deficiency is common with mild clinical consequence. Thus, the lack of MBL may be compensated for by the other PRMs. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26795763
DOI: 10.1007/s00251-016-0903-4
PMCID: PMC4842218

Genes

FCN2
FCN3
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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