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Article

Mannan-binding lectin and its role in innate immunity.

Transfusion medicine (Oxford, England) - 1 Dec 2002

Kilpatrick D C

Abstract excerpt

Mannan-binding lectin (MBL) is a plasma collectin (C-type lectin with a collagen-like domain) and is considered an important component of innate immunity. Circulating MBL is genetically determined for the major part, but plasma concentration is also markedly influenced by nongenetic factors. The carbohydrate-binding ability of MBL can be inhibited by simple sugars like mannose, fucose and N-acetylglucosamine, but...

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Identifiers

PMID: 12473150
DOI: 10.1046/j.1365-3148.2002.00408.x

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