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Article

Nonsynonymous HTR2C polymorphism predicts cortisol response to psychosocial stress I: Effects in males and females.

Psychoneuroendocrinology - 1 Aug 2016

Avery Bradley M, Vrshek-Schallhorn Suzanne

Abstract excerpt

BACKGROUND: Genetic influences on stress reactivity may provide insight into depression risk mechanisms. The C-allele of rs6318, a putatively functional polymorphism located within the HTR2C gene, has been reported to predict greater cortisol and negative affective reactivity to lab-induced stress. However, the potential moderating effect of sex has not been examined despite X-linkage of HTR2C. We hypothesized...

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Identifiers

PMID: 26787298
DOI: 10.1016/j.psyneuen.2015.12.023
PMCID: PMC4948185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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