Article
Cortisol responses to emotional stress in men: association with a functional polymorphism in the 5HTR2C gene.
Biological psychology - 1 Jan 2012
Brummett Beverly H, Kuhn Cynthia M, Boyle Stephen H, Babyak Michael A, Siegler Ilene C, Williams Redford B
Abstract excerpt
The serotonin 5HTR2C receptor has been shown to mediate HPA axis activation during stress. We hypothesized that a functional polymorphism (rs6318) of the 5HTR2C gene would be associated with HPA axis response to a laboratory stress protocol. The present sample consisted of 41 men (22 African Americans, 19 Caucasians). We found that at rest men with the more active rs6318 Ser23 C allele had similar cortisol values...
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