Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex Differences in Stress Susceptibility as a Key Mechanism Underlying Depression Risk

12 Mar 2024

Abstract excerpt

PURPOSE OF REVIEW: Although females are at relatively greater risk for a variety of disorders, including depression, the biological mechanisms underlying this striking health disparity remain unclear. To address this issue, we highlight sex differences in stress susceptibility as a key mechanism potentially driving this effect and describe the interacting inflammatory, hormonal, epigenomic, and...

Topics

Join the communities discussing this publication.

Maternal Mental Health During Pregnancy and Postpartum
Stress Responses and Cortisol
Tryptophan and brain disorders

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38470558
DOI: 10.1007/s11920-024-01490-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex Differences in Stress Susceptibility as a Key Mechanism Underlying Depression RiskPMID 38470558Read ↗

The psychodynamic psychotherapist's guide to the interaction among sex, genes, and environmental adversity in the etiology of depression for women.Semantic proximity Read ↗

Depression in women.Semantic proximity Read ↗

Fetal hormonal programming of sex differences in depression: linking women's mental health with sex differences in the brain across the lifespanSemantic proximity Read ↗

Sex-specific hormone-sensitive regulatory architecture in adolescence as a scaffold for depression vulnerabilitySemantic proximity Read ↗

Anxiety and Depression in Women’s Cardiovascular Health: Risk Modifiers, Mechanisms and Clinical ImplicationsSemantic proximity Read ↗

Emergent research in the cause of mental illness in women across the lifespan.Semantic proximity Read ↗

Unraveling the interaction between stress and genetic risk in psychiatric disorders: Challenges, mechanisms, and new advances.Semantic proximity Read ↗

Microglial function interacts with the environment to affect sex-specific depression risk.Semantic proximity Read ↗

Translating the Transcriptome: Sex Differences in the Mechanisms of Depression and Stress, RevisitedSemantic proximity Read ↗

Genetics of stress response and stress-related disordersSemantic proximity Read ↗

Sex-specific blood-brain barrier alterations and vascular biomarkers underlie chronic stress responses in mice and human depressionSemantic proximity Read ↗

Sex differences in DNA methylation may contribute to risk of PTSD and depression: a review of existing evidence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.