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Article

A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress.

PloS one - 1 Jan 2014

Brummett Beverly H, Babyak Michael A, Williams Redford B, Harris Kathleen Mullan, Jiang Rong, Kraus William E, Singh Abanish, Costa Paul T, Georgiades Anastasia, Siegler Ilene C

Abstract excerpt

Psychosocial stress is well known to be positively associated with subsequent depressive symptoms. Cortisol response to stress may be one of a number of biological mechanisms that links psychological stress to depressive symptoms, although the precise causal pathway remains unclear. Activity of t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25514629
DOI: 10.1371/journal.pone.0114451
PMCID: PMC4267787

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25514629-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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