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Article

Nonsynonymous HTR2C polymorphism predicts cortisol response to psychosocial stress II: Evidence from two samples.

Psychoneuroendocrinology - 1 Aug 2016

Way Baldwin M, Brown Kirk Warren, Quaglia Jordan, McCain Nancy, Taylor Shelley E

Abstract excerpt

The 5-HT2C receptor is the primary serotonin receptor located in the corticotrophin releasing hormone (CRH) neurons of the hypothalamus. These neurons initiate the signaling cascade that culminates in cortisol release. Therefore, genetic variation in the 5-HT2C receptor gene (HTR2C) is a prime candidate for affecting cortisol reactivity to stress. Accordingly, we examined the association of a nonsynonymous...

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Identifiers

PMID: 27211696
DOI: 10.1016/j.psyneuen.2016.04.022

Genes

CRH

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