Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Examining hypothalamic-pituitary-adrenal axis genetic variation on cortisol and alpha-amylase reactivity during an explicit negative-evaluative stress induction.

Stress and health : journal of the International Society for the Investigation of Stress - 1 Dec 2024

Grillo Alessandra R, Starr Lisa R, Vrshek-Schallhorn Suzanne

Abstract excerpt

Prior work consistently links additive genetic variation in the hypothalamic-pituitary-adrenal (HPA) axis-a multilocus genetic profile score (MGPS)-to depression risk in the context of stress exposure. However, despite that HPA MGPS variants were selected based on evidence that they elevate cortisol reactivity, there are surprisingly few tests of whether an HPA MGPS elevates cortisol reactivity to lab-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to alpha-Amylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrocortisone

Share to Hypothalamo-Hypophyseal System

Share to Pituitary-Adrenal System

Share to Saliva

Share to Stress, Psychological

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 39365170
DOI: 10.1002/smi.3484
PMCID: PMC11636444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Examining hypothalamic-pituitary-adrenal axis genetic variation on cortisol and alpha-amylase reactivity during an explicit negative-evaluative stress induction.PMID 39365170Read ↗

Nonsynonymous HTR2C polymorphism predicts cortisol response to psychosocial stress I: Effects in males and females.Semantic proximity Read ↗

Genetics of emotion.Semantic proximity Read ↗

'Negativity bias' in risk for depression and anxiety: brain-body fear circuitry correlates, 5-HTT-LPR and early life stress.Semantic proximity Read ↗

Ambulatory assessment as a means of longitudinal phenotypes characterization in psychiatric disorders.Semantic proximity Read ↗

The Stress Phenotyping Framework: A multidisciplinary biobehavioral approach for assessing and therapeutically targeting maladaptive stress physiology.Semantic proximity Read ↗

Development and cross-tissue validation of a methylation profile score for the cortisol response to stressSemantic proximity Read ↗

Genetic contributions to acute autonomic stress responsiveness in children.Semantic proximity Read ↗

The role of genetic variation in the glucocorticoid receptor (NR3C1) and mineralocorticoid receptor (NR3C2) in the association between cortisol response and cognition under acute stress.Semantic proximity Read ↗

Common oxytocin receptor gene variant interacts with rejection sensitivity to influence cortisol reactivity during negative evaluation.Semantic proximity Read ↗

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders.Semantic proximity Read ↗

HPA-axis multilocus genetic variation moderates associations between environmental stress and depressive symptoms among adolescentsSemantic proximity Read ↗

Genetics of emotion regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.