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Article

Identification of novel loci associated with mycobacterial isoniazid resistance.

Tuberculosis (Edinburgh, Scotland) - 1 Jan 2016

Viswanathan Gopinath, Yadav Sangya, Raghunand Tirumalai R

Abstract excerpt

Despite the known association of several genes to clinical Isoniazid (INH) resistance, its molecular basis remains unknown in ~16% of clinical isolates of Mycobacterium tuberculosis (M. tb). While screening a set of Mycobacterium smegmatis (M. smegmatis) transposon mutants with altered colony morphology for differential susceptibility to INH, we found six resistant mutants and mapped their transposon insertion...

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Identifiers

PMID: 26786650
DOI: 10.1016/j.tube.2015.09.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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