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Article

Enhanced survival of Drosophila Akt1 hypomorphs during amino-acid starvation requires foxo.

Genome - 1 Feb 2016

Slade Jennifer D, Staveley Brian E

Abstract excerpt

Disordered eating includes any pattern of irregular eating that may lead to either extreme weight loss or obesity. The conserved insulin receptor signalling pathway acts to regulate energy balance and nutrient intake, and its central component Akt1 and endpoint effector foxo are pivotal for survival during nutritional stress. Recently generated Akt1 hypomorphic mutant lines exhibit a moderate decrease in lifespan...

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Identifiers

PMID: 26783834
DOI: 10.1139/gen-2015-0113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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