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Article

Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions.

Genetic epidemiology - 1 Feb 2016

Fan Ruzong, Wang Yifan, Yan Qi, Ding Ying, Weeks Daniel E, Lu Zhaohui, Ren Haobo, Cook Richard J, Xiong Momiao, Swaroop Anand, Chew Emily Y, Chen Wei

Abstract excerpt

Genetic studies of survival outcomes have been proposed and conducted recently, but statistical methods for identifying genetic variants that affect disease progression are rarely developed. Motivated by our ongoing real studies, here we develop Cox proportional hazard models using functional regression (FR) to perform gene-based association analysis of survival traits while adjusting for covariates. The proposed...

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Identifiers

PMID: 26782979
DOI: 10.1002/gepi.21947
PMCID: PMC4724326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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