Article

Cox regression increases power to detect genotype-phenotype associations in genomic studies using the electronic health record

2019-04-05

Abstract excerpt

<h4>Background</h4> The growth of DNA biobanks linked to data from electronic health records (EHRs) has enabled the discovery of numerous associations between genomic variants and clinical phenotypes. Nonetheless, although clinical data are generally longitudinal, standard approaches for detecting genotype-phenotype associations in such linked data, notably logistic regression, do not naturally account for the ti...

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Literature Corpus work: a396c8e5-11fa-5506-9166-d705858f4f80
DOI: 10.1101/599910

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